Figure 2.
Ross River virus nsP1 maximum clade credibility tree. Time-measured (MCC tree of 186 RRV genomes following ancestral state reconstruction for aa transitions occurring at nsP1 site 248. The nucleotide substitution rate used to calibrate the tree was 3.21 × 10−4 substitutions/site/year. The four RRV genotypes (G1 to G4) and respective sublineages are indicated with Bayesian posterior probabilities of key nodes (>0.95) provided. Tree branches are colored according to the detected aa transition, namely purple (T to I) or green (I to T). Tree topology and taxa order are identical to each tree represented in main manuscript Fig. 1a. The 17 sequences belonging to the recently emerging G4A-2006 clade containing the signature mutations C T35A, E2 A389T, 6 K A58V, E1 I113V, and E1 V426L are highlighted in the figure.