Table 2.
Baseline symptoms, CMR and laboratory values among patients with or without left ventricular hypertrophy.
| All Patients n = 38 |
No LVH n = 20 |
LVH n = 18 |
p-Value | |
|---|---|---|---|---|
| Age (years) | 41 (27–50) | 36 (23–47) | 44 (34–50) | 0.233 |
| NYHA Class | ||||
| I | 32 (84.2%) | 17 (85%) | 15 (83.3%) | |
| II | 5 (13.2%) | 3 (15%) | 2 (11.1%) | |
| III | 1 (2.6%) | 0 (0%) | 1 (5.6%) | |
| IV | 0 (0%) | 0 (0%) | 0 (0%) | |
| Palpitations | ||||
| no | 32 (84.2%) | 15 (75%) | 17 (94.4%) | |
| yes | 6 (16.8) | 5 (25%) | 1 (5.6%) | |
| CCS Class | ||||
| No Angina | 34 (89.5%) | 20 (100%) | 14 (77.8%) | |
| I | 3 (7.9%) | 0 (0%) | 3 (16.7%) | |
| II | 1 (2.6%) | 0 (0%) | 1 (5.5%) | |
| III | 0 (0%) | 0 (0%) | 0 (0%) | |
| IV | 0 (0%) | 0 (0%) | 0 (0%) | |
| CMR | ||||
| LVMI g/m2 | 70.6 (61–85) | 62.4 (58.7–67.8) | 85 (73.1–114) | 0.001 |
| LVEDV (mL) | 134 ± 29.3 | 120 ± 22.7 | 148 ± 28.9 | 0.003 |
| LVEF (%) | 64.5 ± 7.73 | 63.4 ± 7.44 | 65.6 ± 8.08 | 0.413 |
| Septal T1 (ms) | 973 ± 85.8 | 1015 ± 48.5 | 946 ± 94.9 | 0.039 |
| LGE (%) | 0 (0–0) | 0 (0–0) | 0 (0–6.81) | 0.577 |
| Left atrial volume (mL) | 61.9 (51.6–74.2) | 63.2 (49.4–67.5) | 61.5 (54.6–80) | 0.413 |
| RVEDV (mL) | 133 ± 30 | 124 ± 25.3 | 143 ± 33 | 0.053 |
| RVEF (%) | 55.2 ± 6.78 | 53.6 ± 6.2 | 56.8 ± 7.2 | 0.15 |
| Laboratory markers | ||||
| NT-proBNP (pg/mL) | 62.1 (30.1–166) | 44.5 (28.7–84.2) | 144 (47.8–510) | 0.038 |
| Creatinine (mg/dL) | 0.79 (0.67–0.91) | 0.8 (0.69–0.93) | 0.79 (0.65–0.91) | 0.463 |
| eGFR (mL/min/1.73 m2) | 105 (90.8–120) | 105 (89.1–119) | 104.8 (95.95–121) | 0.858 |
| ACR (mg/g) | 205 (64–282) | 151 (8–239) | 255 (205–1148) | 0.055 |
LVH, left ventricular hypertrophy; CMR, cardiac magnetic resonance imaging; LVMI, left ventricular mass index; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; RVEDV, right ventricular end-diastolic volume; RVEF, right ventricular ejection fraction; eGFR, estimated glomerular filtration rate (calculated using the CKD-EPI equation) [21]; ACR, albumin-to-creatinine ratio. A p-value of <0.05 was considered statistically significant (bold).