Heatmap of selected gut microbiota at the genus level based on relative abundance. Hamsters are fed with NCD, HCD, L-HCAE, H-HACE, L-HCEE, and H-HCEE for 6 weeks, respectively. The blue to red in the picture represents the relative abundance at the genus level that changes from lower to greater. Data represent mean ± SEM of 7–9 hamsters. Asterisks “*”, “**”, and “***” indicate the different levels of associations significant at p < 0.05, p < 0.01, and p < 0.001, respectively, by one-way ANOVA with post hoc Tukey’s analysis. The group comparison information of the genera is displayed on the right. NCD, normal cholesterol diet; HCD, high cholesterol diet; HCAE, Houttuynia Cordata aqueous extract; HCEE, Houttuynia cordata ethanolic extract; L-HCAE, high cholesterol diet containing 1% Houttuynia cordata aqueous extract; H-HCAE, high cholesterol diet containing 5% Houttuynia cordata aqueous extract; L-HCEE, high cholesterol diet containing 1% Houttuynia cordata ethanolic extract; H-HCEE, high cholesterol diet containing 5% Houttuynia cordata ethanolic extract.