Table 2.
Food intake, body weight, and the relative organ weights in hamsters.
| NCD | HCD | L-HCAE | H-HCAE | L-HCEE | H-HCEE | p Value | |
|---|---|---|---|---|---|---|---|
| Daily food intake, g | 8.51 ± 0.24 a | 7.88 ± 0.13 b | 8.42 ± 0.10 a | 8.53 ± 0.15 a | 8.19 ± 0.26 ab | 8.57 ± 0.02 a | <0.01 |
| Body weight, g | |||||||
| Initial (Week 0) | 111.30 ± 2.04 | 112.18 ± 3.13 | 115.00 ± 2.22 | 115.08 ± 2.01 | 111.00 ± 2.02 | 112.38 ± 2.11 | 0.52 |
| Final (Week 6) | 118.00 ± 2.38 | 115.04 ± 2.58 | 123.25 ± 3.31 | 125.08 ± 3.06 | 124.24 ± 3.00 | 124.12 ± 2.04 | 0.05 |
| Body weight gain | 6.70 ± 1.23 | 2.86 ± 1.77 | 8.25 ± 2.46 | 10.00 ± 2.31 | 13.24 ± 2.22 | 11.74 ± 0.54 | 0.05 |
| Relative organ weight, % of body weight (Week 6) | |||||||
| Liver | 3.29 ± 0.10 b | 3.84 ± 0.12 a | 3.85 ± 0.07 a | 3.83 ± 0.06 a | 3.95 ± 0.11 a | 3.92 ± 0.05 a | <0.001 |
| Heart | 0.45 ± 0.03 a | 0.40 ± 0.01 a | 0.37 ± 0.01 b | 0.41 ± 0.01 a | 0.41 ± 0.01 a | 0.38 ± 0.01 ab | 0.02 |
| Kidney | 0.74 ± 0.02 | 0.80 ± 0.01 | 0.72 ± 0.01 | 0.75 ± 0.01 | 0.74 ± 0.02 | 0.74 ± 0.04 | 0.08 |
| Perirenal fat pad | 1.09 ± 0.11 b | 1.08 ± 0.05 b | 1.24 ± 0.06 ab | 1.23 ± 0.09 ab | 1.12 ± 0.05 b | 1.44 ± 0.07 a | <0.01 |
| Testis | 3.97 ± 0.33 | 3.84 ± 0.18 | 3.67 ± 0.18 | 3.75 ± 0.06 | 3.43 ± 0.16 | 3.65 ± 0.28 | 0.52 |
| Epididymal fat pad | 1.70 ± 0.09 | 1.69 ± 0.11 | 1.83 ± 0.07 | 1.81 ± 0.11 | 1.73 ± 0.09 | 1.85 ± 0.14 | 0.75 |
NCD: non-cholesterol diet; HCD: 0.1% cholesterol added into NCD diet; L-HCAE: 1% Houttuynia cordata aqueous extract (HCAE) added into HCD; H-HACE: 5% HCAE added into HCD; L-HCEE: 1% Houttuynia cordata ethanolic extract (HCEE) added into HCD; H-HCEE: 5% HCEE added into HCD. Data represent mean ± SEM of 7–9 hamsters. Means denoted with different superscript letters (a,b) differ significantly, p < 0.05 by one-way ANOVA with post hoc Tukey’s analysis.