Table 2.
Blood biochemical indices in ovariectomized (OVX) rats treated with the Styphnolobium japonicum fruit (SJF) and germinated soybean embryo (GSE) complex extract.
| Parameter | Sham | OVX | +E2 | Complex Extract | ||
|---|---|---|---|---|---|---|
| +Low | +Medium | +High | ||||
| E2 (pg/mL) | 24.68 ± 1.14 | 14.4 ± 0.63 * | 29.72 ± 1.4 ## | 19.86 ± 1.5 | 22.47 ± 2.29 | 33.59 ± 1.88 ## |
| CTx (pg/mL) | 292.97 ± 33.6 | 548.31 ± 28.81 ** | 293.39 ± 21.57 ## | 365.98 ± 49.36 # | 264.35 ± 12.44 ## | 196.32 ± 19.91 ## |
| OC (pg/mL) | 7.44 ± 0.34 | 13.31 ± 0.51 ** | 5.11 ± 0.7 ### | 9.44 ± 0.57 # | 7.57 ± 0.58 ## | 6.29 ± 0.17 ### |
| Ca (mg/dL) | 10.45 ± 0.05 | 10.55 ± 0.55 | 11.15 ± 1.25 | 10.2 ± 0.1 | 10.45 ± 0.05 | 10.8 ± 0.5 |
| P (mg/dL) | 3.65 ± 0.05 | 2.15 ± 0.15 ** | 3.4 ± 0.2 # | 2.3 ± 0.2 | 3.35 ± 0.15 # | 3.75 ± 0.25 ## |
| TG (mg/dL) | 49 ± 5 | 139.25 ± 0.75 ** | 82.9 ± 7.1 # | 94.4 ± 13.6 | 74.05 ± 13.45 | 56.1 ± 2.1 # |
| HDL (mg/dL) | 48.3 ± 1.8 | 41.75 ± 5.25 | 40.03 ± 1.02 | 36.5 ± 1.5 | 43.5 ± 1.5 | 50.4 ± 2.6 |
| LDL (mg/dL) | 5.5 ± 0.5 | 10.5 ± 0.5 ** | 5.5 ± 0.5 ## | 10.5 ± 0.5 | 10 ± 1 | 7.5 ± 0.5 # |
| ALT (U/L) | 70.3 ± 2.8 | 102.05 ± 2.15 * | 88.55 ± 6.15 | 105.95 ± 4.05 | 87.95 ± 9.25 | 63.35 ± 2.05 # |
| LDH (U/L) | 318.25 ± 6.25 | 945.25 ± 80.25 ** | 684.5 ± 79.5 | 396.25 ± 20.25 ## | 210.5 ± 9.5 ### | 227.5 ± 57.5 ### |
OVX rats were orally administered the complex extract at 25 mg/kg (low), 50 mg/kg (medium), and 100 mg/kg for 12 weeks. 17β-estradiol (E2) was used as a positive control. * p < 0.05, ** p < 0.01, vs. the sham group; # p < 0.05, ## p < 0.01, ### p < 0.001, vs. the OVX group. E2, estradiol; CTx, C-terminal telopeptide; OC, osteocalcin; Ca, calcium; P, phosphorus; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ALT, alanine aminotransferase; LDH, lactate dehydrogenase.