Table 1.
Baseline Characteristics (Full Analysis Set)
| Placebo (n = 983) | VIR-2482 450 mg (n = 981) | VIR-2482 1200 mg (n = 992) | Total (n = 2956) | |
|---|---|---|---|---|
| Age at randomization, y | ||||
| Mean (SD) | 39.7 (12.3) | 39.2 (12.5) | 39.6 (11.7) | 39.5 (12.2) |
| Median (range) | 39.0 (18–64) | 38.0 (18–64) | 39.0 (18–64) | 39.0 (18–64) |
| Sex, no. (%) | ||||
| Male | 453 (46.1) | 436 (44.4) | 469 (47.3) | 1358 (45.9) |
| Female | 530 (53.9) | 545 (55.6) | 523 (52.7) | 1598 (54.1) |
| Race, no. (%) | ||||
| American Indian or Alaskan native | 7 (0.7) | 7 (0.7) | 7 (0.7) | 21 (0.7) |
| Asian | 26 (2.6) | 26 (2.7) | 29 (2.9) | 81 (2.7) |
| Black or African American | 166 (16.9) | 154 (15.7) | 176 (17.7) | 496 (16.8) |
| Native Hawaiian or other Pacific Islander | 4 (0.4) | 5 (0.5) | 4 (0.4) | 13 (0.4) |
| White | 758 (77.1) | 752 (76.7) | 747 (75.3) | 2257 (76.4) |
| Multiracial | 6 (0.6) | 17 (1.7) | 11 (1.1) | 34 (1.2) |
| Not reported/unknown | 16 (1.6) | 20 (2.0) | 18 (1.8) | 54 (1.8) |
| Ethnicity, no. (%) | ||||
| Hispanic or Latino | 357 (36.3) | 370 (37.7) | 370 (37.3) | 1097 (37.1) |
| Not Hispanic or Latino | 620 (63.1) | 607 (61.9) | 621 (62.6) | 1848 (62.5) |
| Not reported/unknown | 6 (0.6) | 4 (0.4) | 1 (0.1) | 11 (0.4) |
| Body mass index, kg/m2 | ||||
| Mean (SD) | 27.2 (4.1) | 27.3 (4.1) | 27.4 (4.2) | 27.3 (4.1) |
| Median (range) | 27.2 (18.0–35.0) | 27.5 (18.0–36.6) | 27.7 (18.0–35.1) | 27.5 (18.0–36.6) |
| Injection site location, no. (%) | ||||
| Thigh | 762 (77.5) | 757 (77.2) | 783 (78.9) | 2302 (77.9) |
| Buttock | 219 (22.3) | 223 (22.7) | 207 (20.9) | 649 (22.0) |