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. 2024 Sep 30;16(19):2773. doi: 10.3390/polym16192773

Table 1.

Production of co- or terpolymers with various monomers using Cupriavidus necator strains.

C-Source PHA Type DCW (g/L) PHA (g/L) Content (%) Ref.
Copolymers fructose P (3HB-co-2.1 mol% 3HP) 2.5 - 31 [18]
fructose P (3HB-co-37.7 mol% 3HHx) 1.42 ± 0.05 - 41.1 ± 3.0 [19]
fructose P (3HB-co-64.9 mol% 3HV) 1.5 ± 0.1 - 42.5 ± 3.8 [20]
fructose + ε-CL P (3HB-co-4HB) 7.5 - - [14]
waste rapeseed oil + propanol P (3HB-co-3HV) 14.7 ± 0.3 11.7 ± 0.7 80 [21]
P (3HB-co-3HV) * 138 105 76
fructose + coconut oil P (3HB-co-3HHx) 19 15 - [22]
palm kernel oil + butyrate P (3HB-co-3HHx) * 153–175 113–138 73.3–78.6 [23]
Terpolymers fructose + 4HVA + 5HVA P (3HB-co-3HV-co-4HV-co-5HV) 8.7 ± 0.1 6.3 ± 0.1 72 [12]
fructose + GVL P (3HB-co-3HV-co-4HV) 8.2 ± 0.2 - 80 ± 2 [14]
fructose P (3HB-co-3HV-co-3H4MV-co-3H2MP) 1.67 ± 0.03 0.93 ± 0.03 55.9 ± 1.8 [16]
tung oil P (3HB-co-3HV-co-3HHx) 1.65 0.68 41.2 [24]
fructose + bean oil + DVL P (3HB-co-3HHx-co-5HV) * 66 49 73 this work
fructose + bean oil + DVL P (3HB-co-3HHx-co-5HV) * 90 69 77 this work

Abbreviation: ε-CL, ε-caprolactone; GVL, γ-valerolactone; 4HVA, 4-hydroxyvaleric acid; 5HVA, 5-hydroxyvaleric acid; DVL, δ-valerolactone; 3HB, 3-hydroxybutyrate; 3HV, 3-hydroxyvalerate; 3H4MV, 3-hydroxy-4-methylvalerate; 3H2MP, 3-hydroxy-2-methylpropionate; 3HP, 3-hydroxypropionate; 3HHx, 3-hydroxyhexanoate; 4HB, 4-hydroxybutyrate; 4HV, 4-hydroxyvalerate; 5HV, 5-hydroxyvalerate. PHA with the mark * was produced through fed-batch fermentation.