Table 1.
Characteristics of 137 RTRs classified by the presence of MASLD 1.
| All (n = 137) | HSI < 36 (n = 102) | HSI > 36 (n = 35) | |
|---|---|---|---|
| Demographics | |||
| Male/female | 80/57 | 60/42 | 20/15 |
| Age, year | 49.20 ± 12.46 | 48.87 ± 12.52 | 50.17 ± 12.38 |
| Height, cm | 161.91 ± 8.51 | 161.65 ± 8.22 | 162.67 ± 9.39 |
| Body weight, kg | 62.79 ± 12.68 | 59.21 ± 10.73 | 73.23 ± 12.27 * |
| Body mass index, kg/m2 | 23.83 ± 3.64 | 22.56 ± 3.01 | 27.52 ± 2.70 * |
| WC, cm | 83.72 ± 9.53 | 80.95 ± 8.67 | 92.04 ± 6.84 * |
| Renal transplant time, year | 8.34 ± 7.01 | 8.03 ± 7.26 | 9.25 ± 6.21 |
| Tacrolimus/cyclosporine used | 89/42 $ | 66/30 | 23/12 |
| Deceased/living donors | 96/41 | 71/31 | 25/10 |
| Laboratory | |||
| Albumin, g/dL | 4.32 ± 0.31 | 4.35 ± 0.29 | 4.21 ± 0.33 * |
| Blood urea nitrogen, mg/dL | 24.07 ± 10.34 | 24.14 ± 10.16 | 23.85 ± 11.02 |
| Creatinine, mg/dL | 1.43 ± 0.70 | 1.41 ± 0.71 | 1.46 ± 0.66 |
| AC-sugar, mg/dL | 99.94 ± 31.79 | 94.98 ± 17.31 | 114.26 ± 53.37 * |
| HbA1c, % | 6.04 ± 0.84 | 5.90 ± 0.77 | 6.45 ± 0.90 * |
| Uric acid, mg/dL | 6.11 ± 1.28 | 6.10 ± 1.16 | 6.16 ± 1.60 |
| Total cholesterol, mg/dL | 207.4 ± 46.27 | 204.19 ± 46.30 | 216.66 ± 45.57 |
| Triglycerides, mg/dL | 162.49 ± 127.99 | 147.88 ± 122.05 | 203.83 ± 136.99 * |
| HDL-C, mg/dL | 53.78 ± 17.10 | 54.98 ± 17.44 | 50.46 ± 15.89 |
| LDL-C, mg/dL | 119.96 ± 37.57 | 117.69 ± 37.57 | 126.43 ± 37.35 |
| AST, U/L | 25.21 ± 7.84 | 24.32 ± 6.82 | 27.80 ± 9.93 |
| ALT, U/L | 23.60 ± 17.87 | 18.18 ± 8.75 | 39.40 ± 26.53 * |
| Insulin, mU/L | 14.18 ± 50.77 | 7.70 ± 11.07 | 31.40 ± 94.21 |
| hs-CRP, mg/dL | 6.04 ± 14.61 | 4.67 ± 12.56 | 9.83 ± 18.91 * |
| Dietary intake | |||
| Energy, kcal/day | 1810.91 ± 399.53 | 1821.48 ± 390.94 | 1780.12 ± 428.00 |
| Carbohydrate, g/day | 198.18 ± 55.84 | 200.49 ± 55.19 | 191.45 ± 57.98 |
| Carbohydrate, % energy | 43.60 ± 7.31 | 43.87 ± 7.29 | 42.81 ± 7.42 |
| Protein, g/day | 68.02 ± 14.73 | 67.44 ± 15.02 | 69.72 ± 13.91 |
| Protein, % energy | 15.23 ± 2.56 | 14.94 ± 2.36 | 16.06 ± 2.95 |
| Fat, g/day | 82.33 ± 21.64 | 82.98 ± 21.84 | 80.44 ± 21.22 |
| Fat, % energy | 40.99 ± 6.23 | 41.08 ± 6.44 | 40.75 ± 5.66 |
| Others | |||
| eGFR, mL/min/1.73 m2 | 55.48 ± 20.40 | 56.52 ± 21.38 | 52.45 ± 17.15 |
| SBP, mmHg | 133.94 ± 16.38 | 133.28 ± 15.30 | 135.88 ± 19.31 |
| DBP, mmHg | 77.72 ± 12.05 | 77.47 ± 11.87 | 78.47 ± 12.68 |
| CCI | 2.01 ± 1.17 | 2.03 ± 1.19 | 1.94 ± 1.11 |
| HOMA-IR | 3.37 ± 13.56 | 1.62 ± 1.18 | 8.34 ± 26.18 * |
| HSI | 32.39 ± 6.03 | 29.67 ± 3.66 | 40.33 ± 4.31 * |
Abbreviations: RTRs, renal transplant recipients; MASLD, metabolic-associated steatotic liver disease; HSI, hepatic steatosis index; WC, waist circumference; AC-sugar, preprandial blood glucose; HbAlC, glycated hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase; hs-CRP, high-sensitivity C-reactive protein; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; CCI, Charlson comorbidity index; HOMA-IR, homeostasis model assessment-insulin resistance. 1 Values are presented as the mean ± standard deviation or number, as appropriate. Statistical analyses were conducted using Student’s t-test, Wilcoxon rank sum test, and chi-square test as appropriate. * p < 0.05. $ No records of six patients.