FIG. 6.
MV-HXL infectivity for MC38-CEA cells is inhibited by cleavage of the displayed scAb or antibody preadsorption of cell surface CEA. Vero cells (as a control) and MC38-CEA cells were infected with MV or MV-HXL (MOI, 1), untreated or pretreated with 10 μg of factor Xa/ml. Also, cells were pretreated with 10 μg of αCEA COL1 antibody/ml and then infected with MV or MV-HXL (MOI, 1). Virus released from the cells by freeze-thaw 72 h postinfection was quantified by TCID50 titration on Vero cells.