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. 2024 Oct 10;13:285. doi: 10.1038/s41377-024-01612-0

Fig. 1. Experimental implementation of EDF-RIM.

Fig. 1

a Optical layout of the experimental system. Speckles are generated either with a diffuser or a spatial light modulator. The detection branch comprises a 4f optical relay (fR1, fR2) which includes an electrically tunable lens to perform a rapid focal sweep placed in a pupil plane. b Temporal scheme of an acquisition sequence. the top line represents the z-plane conjugated to the camera which is rapidly scanned in one integration time. c, d Example of an illumination speckle in the x, y and x, z planes. The insets display the speckle auto-covariance function ΓEDF(r) ≔ ΓS(x, y, 0) and ΓS(x, 0, z). e Comparison between the 2D PSF, h2D(r), of the wide field microscope and the EDF-PSF, h(r), which is obtained from the integral of the 3D-PSF along the z-axis