Fig. 1.

Imaging preprocessing. (A) Overview of QSM processing. QSM is reconstructed from 3D gradient echo phase images with different TE. There are three main steps in the processing from the raw phase image to QSM; 1 unwrapping 2 background phase removal by high-pass filtering, 3 inverse problem solution by performing a dipole deconvolution. (B) Automatic ROI creation using SARM atlas. SARM atlas in NMT space was inversely transformed into each subject’s space (from (d) to (c)) using output from alignment of a subject’s T1w image to NMT (from (a) to (b)).