Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Overview of two DNA methylation inhibitors.
| Drug name | Chemical name | Structure | Main treatment | First marketed year |
|---|---|---|---|---|
| Azacitidine | 4-amino-1-β-D-ribofuranosyl-1,3,5-triazine-2(1H)-one | C8H12N4O5 | Myelodysplastic syndromes (MDS), Acute Myeloid Leukemia (AML), and Chronic Myeloid Leukemia | 2004 |
| Decitabine | 5-azacitidine-2′-deoxycytidine | C8H12N4O4 | Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) | 2012 |
