Figure 2.

Details of the interface of hCap2_HR1 trimer.A and B, in the N-lobe, helices α1 and α1′ fold back toward and form intramolecular interaction with helices α2, α3-1, and α3-2 in chain A and helices α2′ and α3′ in chain B, respectively, thereby forming two anti-parallel coiled coils. C–E, details of the intermolecular interactions between the two N-lobes. F, G, and H, details of the intermolecular interactions between the two C-lobes. Images of structures were generated using PyMOL. HR, homologous region.