Figure 2.
Adjusted hazard ratio for recurrent P vivax parasitaemia between day 7 and day 180 for total dose of primaquine by age (A) and 14-day vs 7-day primaquine stratified by total dose in children younger than 15 years (B)
A low total dose of primaquine was about 3·5 mg/kg, and a high total dose of primaquine was about 7 mg/kg. Cox proportional hazards models adjusting for age, sex (male or female), and (log10) baseline parasite density, with shared frailty by study site. P vivax=Plasmodium vivax. *Adjusted hazard ratio relative to no primaquine. †Adjusted hazard ratio relative to 7 days of primaquine.