Table 3.
Comparison of Clinical and Radiotherapy Characteristics among Study Groups
| RT dose | P value | |||
|---|---|---|---|---|
| 30 Gy/10 F Mean ± SD (%) |
30 Gy/5 F Mean ± SD (%) |
|||
| Age | Years | 48.6 ± 15.4 (27-67)* | 45 ± 13.3 (27-67)* | 0.602 |
| Sex | Female | 10 (50) | 9 (45%) | 0.752 |
| Male | 10 (50) | 11 (55) | ||
| Primary Pathological subtype | Anaplastic | 3 (15) | 1 (5) | 0.292 |
| GBM** | 17 (85) | 19 (95) | ||
| Biopsy | 8 (40) | 8 (40) | ||
| Primary surgical resection | Complete | 3 (15) | 5 (25) | 0.251 |
| Partial | 9 (45) | 7 (35) | ||
| Cerebellum | 0 (0) | 2 (10) | ||
| Frontal | 7 (35) | 7 (35) | ||
| Fronto-Parietal | 2 (10) | 3 (15) | ||
| Fronto-Temporal | 5 (25) | 0 (0) | ||
| Occipital | 0 (0) | 2 (10) | 0.134 | |
| Parietal | 2 (10) | 2 (10) | ||
| Site of recurrence | Parieto-Occipital | 0 (0) | 1 (5) | |
| Parieto-Temporal | 2 (10) | 0 (0) | ||
| Temporal | 2 (10) | 3 (15) | ||
| Relapse performance status | 73.5± 13.1 (50-90)* | 74±11.4 (50-90)* | 0.919 | |
| Steroids intake | No | 8 (40) | 11 (55) | 0.343 |
| Yes | 12 (60) | 9 (45) | ||
| Number of lesions | Single | 17 (85) | 18 (90) | 0.082 |
| 2 lesions | 3 (15) | 2 (10) | ||
| PTV (CC) | 35.9±25.3 (8-80)* | 27±15.7 (4.8-57)* | 0.445 | |
| Interval for re-irradiation (months) | 8.2± 1.5 (6.6-11.5)* | 9.2±1.3 (7.2-10.9)* | 0.401 | |
SD, standard deviation; *, range; GPM, Glioblastoma multiform; PTV, Planning target volume CC, Cubic centimeter