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. 2024 Sep 5;25(10):6503–6514. doi: 10.1021/acs.biomac.4c00672

Figure 2.

Figure 2

Optimization of single emulsion solvent evaporation method for encapsulation of ABT-737 and Purvalanol A. (A) Schematic overview of the preparation process of ABT PLGA NPs and Purvalanol PLGA NPs as intermediate formulations for optimization of process parameters for the dual-drug entrapment in PEGylated NPs. (B,C) Characterization of ABT PLGA NPs and Purvalanol PLGA NPs, respectively, in terms of the amount of drug entrapped (μg of drug/mg of NP), loading efficiency (LE, %), nanoparticle size (nm), and polydispersity index (PdI). Data are presented as mean values of n = 3.