FIG. 3.

In vitro growth characteristics of SIVagm variants in a human T-cell line and macrophages. SIVagm viruses recovered from brain (sab-4br), CSF (sab-4CSF), and LNs (sab-4ln) were normalized for p27 (nanograms per milliliter) and used to infect Molt4 clone 8 cells (A) and human macrophages (B). Well-characterized isolates [SIVagm(tyo-1), SIVagm(MJ8), and SIVagm(gri-1)] were run for comparison. HIV-1/Ba-L is not shown in panel B due to the very high virus peak at day 6 (1,200 ng/ml). Ag, antigen.