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Study design. aPatients from ORION-3 did not receive any drug administration on Day 1. Only patients on placebo in ORION-9, ORION-10, and ORION-11 received an active inclisiran injection at Day 1, while patients who received inclisiran in those trials received blinded placebo at this visit; bEOS is either day 1080 or ≥ 90 days following the last dose of inclisiran. D, Day; EOS, end-of-study.
