Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Patient disposition in the ORION-8 trial aOne patient from the inclisiran arm of pivotal trials ORION-9, ORION-10, and ORION-11 did not receive any injection in ORION-8. bThe primary reasons for discontinuation were ORION-3 rollover patients not offered to complete the full study period (8.3%), death (5.0%), withdrawal of consent (4.8%), lost to follow-up, mostly during the COVID-19 pandemic period (3.1%), other (2.3%), and adverse events (1.4%).
