Figure 5.

Glycosaminoglycan accumulation with age in the NHP female heart's left ventricle. A) Histological staining of glycosaminoglycans and hematoxylin and eosin in heart tissue, B) respective quantification of glycosaminoglycan with age (depicted ages of GAG accumulation in light gray and of fast accumulation in dark gray), and C) variation of left ventricle cardiomyocyte size with age (each dot represents the mean ± 95% confidence interval for each individual; gray line the age of the vertice calculated from the quadratic curve). GAG – glycosaminoglycan; HE – hematoxylin and eosin staining.