Table 1.

Cardiovascular phenotypes associated with genetic variance in glycosaminoglycan metabolism, synthesis, and degradation.

Phenotype	Genes	References
Abnormal QRS Duration	CHPF	[99]
Irregular Ascending Aorta	HAS 2	[100, 101, 102, 103]
Pulse Pressure Linked To LV Hypertrophy	HAS 2	[104]
Coronary Artery Disease	CHST3	[105]
Small Vessel Stroke	CHST3	[106]
Altered Diastolic Blood Pressure	UST and CHST12	[107, 108, 109, 110]
Atrial Fibrillation	UST and SULF2	[111, 112, 113, 114, 115]
Resistance Hypertension	CHST1	[116]
Abnormal Pulse Pressure	CHST11	[117]
Carotid Artery Intima‐Media Thickness	CHST11 and HS6ST3	[118]
Coronary Artery Disease	CHST12	[119]
Impaired Systolic Blood Pressure	CHST12, NAGLU and HS6ST3	[108, 109, 120, 121, 122]
Abnormal Rate Variability Measurement	HS6ST1	[123]
Irregular Pulse Pressure Measurement	HS6ST3	[117]