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. 2024 Jun 10;230(4):e971–e984. doi: 10.1093/infdis/jiae273

Figure 3.

Figure 3.

Reverse cumulative distribution curves of (A and B) anti-Shigella flexneri 2a O-antigen serum IgG as measured by ELISA: (A) altSonflex3M group up to 1 month after injection 2; (B) altSonflex6M group up to 1 month after injection 2; and (C and D) bactericidal antibody activity as measured by SBA in a subset of participants: (C) altSonflex3M group up to 1 month after injection 2; (D) altSonflex6M group up to 1 month after injection 2. Abbreviations: altSonflex3M, participants randomized to receive altSonflex1-2-3 vaccine at 3-month interval; altSonflex6M, participants randomized to receive altSonflex1-2-3 vaccine at 6-month interval; ELISA, enzyme-linked immunosorbent assay; EU, ELISA unit; IgG, immunoglobulin G; n, number of participants with available data at a given time point; SBA, serum bactericidal assay.