Table 3.

Descriptive statistics for ADI-R, ADOS, BOSA and CBCL

	24 months				36 months
	TD group		NF1 Group		TD group		NF1 Group
	n	Mean [SD]	n	Mean [SD]	n	Mean [SD]	n	Mean[SD]
Autism Diagnostic Interview—Revised (ADI-R) Diagnostic Algorithm
Qualitative Abnormalities in Reciprocal Social Interaction (A)		N/A		N/A	18	0.94 [1.00]	30	5.23 [4.79]
Qualitative Abnormalities in Communication (B)					18	0.67 [0.97]	30	5.03 [4.42]
Restricted, Repetitive and Stereotyped Patterns of Behaviour (C)					18	0.39 [0.61]	30	2.13 [2.60]
Abnormality of Development Evident at or Before 36 Months (D)					18	0.06 [0.24]	30	1.83 [1.34]
Meeting threshold for autism on ADI-R					18	0 [0%)]	30	5 [17%]
Not meeting threshold for autism on ADI-R					18	18 [100%]	30	25 [83%]
Autism Diagnostic Observation Schedule-2 (ADOS-2)
Module (n) (Toddler/Module 1/Module 2)	24	24/0/0	24	21/3/0	20	0/0/20	17	0/16/1
Total scores	24	3.67 [1.95]	24	8.08 [6.64]	20	4.35 [3.42]	17	4.47 [3.86]
Social Affect scores	24	3.13 [1.80]	24	6.83 [5.75]	20	3.60 [2.84]	17	3.65 [3.02]
Restrictive and Repetitive Behaviour scores	24	0.54 [0.72]	24	1.25 [1.29]	20	0.80 [0.95]	17	0.82 [1.24]
Number reaching threshold for Autism Spectrum Disorder or Autism on ADOS-2	24	0 [0%]	24	11 [46%]	20	5 [25%]	17	4 [24%]
Brief Observation of Symptoms of Autism (BOSA-MV)
Module (Toddler/Module 1)	0	0/0	3	2/1	0	0/0	12	0/12
Total scores			3	12.33 [4.93]			12	8.17 [2.66]
Algorithm scores			3	6.00 [2.00]			12	4.42 [1.44]
Number reaching threshold for Autism Spectrum Disorder on the BOSA			3	2 [67%]			12	5 [42%]
ADOS/BOSA combined
Number of participants reaching threshold for Autism	24	0 [0%]	27	13 [48%]	20	5 [25%]	29	9 [31%]
Number of participants not reaching threshold for Autism	24	24 [100%]	27	14 [52%]	20	15 [75%]	29	20 [69%]
Number of participants reaching threshold for Autism on both ADI-R and ADOS/BOSA		N/A		N/A	18	0 [0%]	29	4 [14%]
Child Behavior Checklist ADHD subscale
T score	22	51.86 [2.49]	27	55.56 [7.84]	21	51.10 [1.45]	28	57.14 [6.88]