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. 2024 Oct 15;16:141. doi: 10.1186/s13148-024-01759-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 6 — Genomic plots of selected genes. Genomic plots of selected CpG-gene pairs eligible as epigenetically modifiable target genes with mapping of genes and CpG sites, Log2FC of methylation, correlation between methylation and expression, mapping of transcription factors binding sites (ChIP-seq ENCODE) as well as differences in expression and methylation between hCiCs and hPACs. A Genomic plots of cg07730609-CHAD and cg20441426-MGP with lower expressed in hCiCs relative to hPACs. B Genomic plots of cg25834415-KIF1A and cg23425348-NKX2-2 with higher expressed in hCiCs relative to hPACs