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Mutants with decreased susceptibility to DHB
| Escherichia coli MG1655 mutants | DHB MIC (μg mL−1) | |
|---|---|---|
| Location | Mutation | |
| Escherichia coli MG1655 (parental) | N/A | 1 |
| ubiA180 | Non-synonymous substitution Alanine → Proline |
16 |
| Intergenic (+3/–10) | Substitution G → A |
8 |
| ubiA170 | Non-synonymous substitution Tryptophan → Arginine |
16 |
| ubiA166 | Non-synonymous substitution Proline → Leucine |
8 |
| ubiC (140–142/165) | Insertion of mobile element Δ2bp :: IS186 + 8 bp :: Δ1bp |
8–16 |
