Table 1.

Characteristics of the intention to treat population at randomization. Data are reported as count (%), mean (SD) or median (25th-75th percentiles)

Characteristic	Hypothermia (n = 294)	Normothermia (n = 306)
Age – years mean (SD)	59.9 $\pm$ 11.9	58.3 $\pm$ 12.2
Male sex – no. (%)	250 (85.0)	263 (85.9)
Medical History
Chronic heart disease—no. (%)	17 (6.0)	17 (5.8)
Arterial hypertension—no. (%)	106 (37.3)	87 (29.9)
Diabetes – no. (%)	51 (17.3)	39 (12.7)
Previous myocardial infarction – no. (%)	41 (14.4)	37 (12.7)
Charlson Comorbidity index – median (IQR)	2.0 [1.0—4.0]	3.0 [1.0—4.0]
Characteristics of the cardiac arrest
Location of arrest
- Home – no. (%)	146 (49.7)	151 (49.3)
- Public place – no. (%)	115 (39.1)	122 (39.9)
- Other – no. (%)	33 (11.2)	33 (10.8)
Bystander witnessed arrest – no. (%)	294 (100.0)	306 (100.0)
Bystander CPR performed – no. (%)	247 (84.0)	264 (86.3)
Epinephrine, mg – median (IQR)	1 (0–2)	1 (0–2)
Number of defibrillation—median (IQR)	3 (1–4)	3 (1–4)
First monitored rhythm
VF – no. (%)	258 (87.8)	259 (84.6)
VT – no. (%)	36 (12.2)	47 (15.4)
Admission FOUR Motor Score of 0 – no. (%)	230 (84.6)	229 (82.7)
Time from cardiac arrest to ALS—minutes, mean (IQR)	9.4 $\pm$ 3.1	9.3 $\pm$ 2.9
Time from cardiac arrest to sustained ROSC – minutes, median (IQR)	22.0 [15.0—32.0]	22.0 [16.0—32.0]
Time from arrest to randomization – minutes, median (IQR)	102.9 $\pm 42.1$	103.1 $\pm 41.9$
Clinical characteristics on admission
Temperature on admission – median (IQR)	35.2 [34.3—36.1]	35.2 [34.4—36.0]
Serum lactate—mmol/L, median (IQR)	4.1 (2.4–6.6)	4.0 (1.9–6.6)
Shock on admission—no. (%)	63 (21.4)	72 (23.5)
ST-elevation myocardial infarction—no. (%)	141 (48.6)	138 (45.4)
CAHP score—mean (SD)	129 $\pm$ 36	124 $\pm$ 37

CPR, Cardiopulmonary resuscitation; GCS, Glasgow Coma Scale; CAHP, Cardiac Arrest Hospital Prognosis; FOUR, Full Outline of UnResponsiveness; ALS, Advanced life support