Table 5.
Molecular subtype | IPAQ | Patients | Events | Median survival time in months (95% CI) | 6-month survival rate (95% CI) | 12-month survival rate (95% CI) | 24-month survival rate (95% CI) | 36-month survival rate (95% CI) |
---|---|---|---|---|---|---|---|---|
HRpos: Luminal A-like | low | 75 | 44 | 28.2 (20.9, 41.6) | 0.94 (0.89, 1.00) | 0.80 (0.71, 0.90) | 0.55 (0.44, 0.68) | 0.44 (0.33, 0.58) |
moderate | 425 | 251 | 28.6 (25.1, 33.5) | 0.90 (0.88, 0.93) | 0.79 (0.75, 0.83) | 0.56 (0.51, 0.61) | 0.42 (0.38, 0.48) | |
high | 49 | 26 | 37.3 (30.2, NA) | 0.96 (0.90, 1.00) | 0.89 (0.81, 0.99) | 0.69 (0.57, 0.84) | 0.50 (0.37, 0.68) | |
HRpos: Luminal B-like | low | 18 | 14 | 23.8 (11.3, NA) | 0.89 (0.75, 1.00) | 0.65 (0.46, 0.92) | 0.47 (0.29, 0.78) | 0.30 (0.14, 0.62) |
moderate | 194 | 136 | 24.0 (19.9, 30.0) | 0.90 (0.86, 0.95) | 0.71 (0.65, 0.78) | 0.49 (0.43, 0.57) | 0.33 (0.26, 0.41) | |
high | 32 | 16 | 36.1 (24.6, NA) | 0.97 (0.91, 1.00) | 0.84 (0.72, 0.98) | 0.71 (0.56, 0.89) | 0.53 (0.38, 0.74) | |
HER2pos | low | 26 | 10 | 39.3 (27.4, NA) | 0.96 (0.89, 1.00) | 0.83 (0.70, 1.00) | 0.74 (0.58, 0.94) | 0.56 (0.38, 0.84) |
moderate | 217 | 105 | 41.0 (35.4, 51.7) | 0.95 (0.92, 0.98) | 0.82 (0.76, 0.87) | 0.64 (0.57, 0.71) | 0.54 (0.47, 0.62) | |
high | 35 | 17 | 40.0 (24.8, NA) | 0.85 (0.74, 0.98) | 0.85 (0.74, 0.98) | 0.68 (0.53, 0.87) | 0.51 (0.35, 0.74) | |
TNBC | low | 11 | 10 | 9.8 (3.2, NA) | 0.54 (0.31, 0.93) | 0.36 (0.16, 0.79) | 0.18 (0.05, 0.63) | NA |
moderate | 104 | 79 | 13.0 (10.8, 18.2) | 0.80 (0.72, 0.88) | 0.54 (0.45, 0.65) | 0.30 (0.22, 0.41) | NA | |
high | 20 | 15 | 15.0 (10.6, NA) | 0.94 (0.83, 1.00) | 0.61 (0.43, 0.88) | 0.20 (0.07, 0.52) | NA |
HER2pos Human epidermal growth factor receptor 2 positive, HRpos Hormone receptor-positive, TNBC Triple negative breast cancer, IPAQ International Physical Activity Questionnaire, CI Confidence interval, NA Not applicable – could not be calculated