Fig. 5.

Early tissue hemodynamics changes predict the antiangiogenic therapy effect. The changes at day three after treatment (Δ = Day 3 - Day 0) of the in vivo recovered blood flow index (BFI) and total hemoglobin concentration (THC) parameters were observed to correlate with the ex vivo tumor characteristics: A. The initial tumor BFI change was observed to correlate with the histology recovered tumor micro vessel density (MVD). B. The initial tumor THC was observed to correlate with the extracted tumor weight (TW). Individual data points for responders are shown in red, non-responders in blue and controls in black. r is the Pearson correlation coefficient.