Inducers of the lytic cycle of EBV concomitantly induce apoptosis. (A and B) Western blot analysis of 50 μg of total cellular RIPA lysates prepared from Mutu-I cells, untreated (−) or treated for 48 h with TGF-β1, anti-IgM, or PMA as described in Materials and Methods. (A) Probed with EE human serum; (B) probed with a polyclonal anti-PARP rabbit serum. (C) Cell cycle distribution of samples taken from the same experiment. Cells were fixed, stained for DNA content with PI, and analyzed by flow cytometry.