FIG. 2.

Inhibition of caspase activity does not block induction of the lytic cycle. Mutu-I cells were pretreated with the pan-caspase inhibitor ZVAD for 1 h prior to induction of the lytic cycle by TGF-β, anti-IgM, or PMA. Apoptosis (A) and induction of lytic antigens (B) were assayed by Western blotting and probing with an anti-PARP rabbit serum or serum EE, respectively. ZVAD alone had no obvious effect in the untreated cells (−) (first two tracks in both panels).