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Locations of TP63 variants identified in patients with immune system abnormalities. The domain structure is illustrated based on the TAp63α isoform [34]: TA—transactivation domain, DBD —DNA binding domain, OD—oligomerization domain, SAM—sterile-alpha motif domain, TI—transactivation inhibitory domain. Figures were created and modified by using the MutationMapper (https://www.cbioportal.org/mutation_mapper, accessed on 9 September 2024) [35].
