FIG. 1.

Stereoview of cryoEM reconstructions showing native CAV21 (a), complex of CAV21 with ICAM-1 domains D1 to D5 (b), complex of HRV16 with ICAM-1 domains D1 and D2 (c), and complex of poliovirus 1 (Mahoney strain) with CD155 domains D1 to D3 (d). CAV21 is purple, HRV16 is green, poliovirus 1 is blue, ICAM-1 is yellow, and CD155 is red. In panel b, five domains of ICAM-1 can be seen; in panel c, only two domains of ICAM-1 can be seen. All three domains of CD155 are observed in panel d. One icosahedral asymmetric unit is outlined in black on each of the four image reconstructions.