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Golgi proteins affected by acute and prolonged GARP depletion
| Affected proteins | Early defects (up to six hours of VPS54 depletion) | Late defects (more than six hours of VPS54 depletion or KO) |
|---|---|---|
| TGN proteins | TGN46 ATP7A TMEM87A CPD |
|
| Golgi SNAREs | GS15/BET1L | GS28/GOSR1 |
| Golgi enzymes | C1GALT1 | B4GALT1 MGAT1 GALNT2 |
| Calcium homeostasis maintenance proteins | SDF4 ATP2C1 |
|
| ARFGEFs | GBF1 | BIG1 |
| Coats/adaptors/accessory proteins | β-adaptin GGA2 COPB2 |
