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(A) Schematic overview of steroid enrichment and strain isolation experiments. (B) HCS.1 strain colonies on cortisol-infused media. (C) HCS.1 strain colonies on progesterone-infused media. Scale bar, 200 μm. (D) Microbial community profile of the final steroid hormone enrichment passage based on16S rRNA amplicon sequencing. (E) Circular representation of the HCS.1 genome.
