Fig. 12. UL116 and gL share similar binding sites on gH.
a, Front (top) and back (bottom) views of UL116 (left), gL in the trimer (middle), and gL in the pentamer (right) bound to gH. UL116 and gL are depicted as ribbon diagrams, while gH is shown as a surface model. The calculated buried surface area of each interaction pair is indicated below each structure. b, Comparison of the UL116 binding footprint on gH with that of gL from the trimer (left) and the pentamer (right). The UL116 binding footprint is highlighted in purple, gL from the trimer in blue, and gL from the pentamer in green, with the overlapping region shown in orange. The buried surface area of the overlapping region is indicated.