FIG. 2.

Binding affinities of p11C and p41A for Mamu-A∗01 are equivalent. Live-cell peptide binding assays were performed by measuring the inhibition of binding of the iodinated index p11C analog peptide (ATPYDINQM) (8). Varying concentrations of unlabeled p11C (●), p41A (▴), or control p11B (■) test peptides were utilized in this assay. The 50% inhibitory concentrations for both p11C and p41A were determined to be 10 nM in this assay. Results shown here are representative of assays performed three times.