Table 1.

New formulations of paclitaxel and docetaxel approved or in clinical development

Product	Developer	Taxane	Formulation	Administration	Ref.
Abraxane	Abraxis BioScience	paclitaxel	HSA nanoparticle	i.v.	[20]
Lipusu	Luye Pharmaceuticals	paclitaxel	Liposome lecithin and cholesterol	i.v.	[21]
Genexol-PM	Samyang Corp.	paclitaxel	o(LA)8-PTX, PEG-b-PLA micelle	i.v.	[15,22]
Nanoxel	Samyang Corp.	docetaxel	PEG-b-PLA micelle	i.v.	[23]
LEP-ETU	Insys Therapeutics	paclitaxel	Liposome dioleoyl-sn-glycero-3-phosphocholine, cholesterol, and cardiolipin	i.v.	[21]
EndoTAG-1	Medigene AG	paclitaxel	cationic liposome (dioleoyl-3-trimethylammonium propane/dioleoyl-sn-glycero-3-phosphocholine)	i.v.	[24]
PTX-LDE	Palantir Technologies	paclitaxel	Lipid core nanoparticle protein-free liposome phosphatidylcholine, cholesterol and triolein), mimicking LDL	i.v.	[25]
LE-DT	NeoPharm	docetaxel	Liposome dioleoyl-sn-glycero-3-phosphocholine, cholesterol, cardiolipin, alpha-tocopheryl succinate	i.v.	[26]
ATI-1123	Azaya Therapeutics	docetaxel	Liposome phospholipids, cholesterol, human serum albumin, saccharose	i.v.	[24]
Paclical	Oasmia Pharmaceutical	paclitaxel	Polymeric micelle N-retinoyl-L-cysteic acid methyl ester sodium salt, retinoid derivatives	i.v.	[27]
Paclitaxel polymer micelles	Shanghai Yizong	paclitaxel	Polymeric micelle mPEG-PDLLA (methoxy polyethylene glycol 2000-polylactide amphiphilic block copolymer)	i.v.	[16]
Liporaxel (DHP107)	Daehwa Pharmaceutical	paclitaxel	lipid-based oral formulation monoolein, tricaprylin, polysorbate 80	oral	[17,18]
Oraxol	Athenex	paclitaxel	lipid-based oral capsule combination with encequidar	oral	[28]