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Treatment medication choices. Immunosuppressants are considered first-line therapy in RA-ILD, with mycophenolate mofetil, azathioprine, and rituximab consistently shown to improve lung function in RA-ILD in observational studies. Evidence also supports abatacept as a treatment choice, particularly for patients with high articular burden. HRCT, high-resolution computed tomography; ILD, interstitial lung disease; PFT, pulmonary function testing.
