Table 1.
IFI, n (%)α | |
- Aspergillus spp. | 13 (62) |
- Candida spp. | 2 (10) |
- Cryptococcus spp. | 5 (24) |
- Fusarium spp. | 1 (5) |
- Histoplasma spp. | 1 (5) |
- Pneumocystis jiroveci | 1 (5) |
Site of infection, n (%) | |
- Blood | 3 (14) |
- CNS | 2 (10) |
- Lung | 20 (95) |
- Sinus | 1 (5) |
- Skin/skin structure | 1 (5) |
- Multiple sites of infectionß | 4 (19) |
One patient identified through indirect testing methods (e.g. Beta-D-glucan)
These include: 58-year-old male with Candida albicans in ascitic fluid, blood, and lungs, along with Aspergillus fumigatus in the ascitic fluid who deceased 13 days after IFI diagnosis; 65-year-old male with disseminated Cryptococcus neoformans in cerebrospinal fluid and lungs who resumed ibrutinib two months after IFI diagnosis; 59-year-old male with Cryptococcus spp in his lungs and blood who resumed ibrutinib two weeks after IFI diagnosis; 65-year-old male with Aspergillus spp pneumonia and a CT head concerning for CNS involvement who deceased one day after IFI diagnosis