Parameters (factors) and levels evaluated by DOE.
| Factor | Symbol | Level (−) | Level (+) |
|---|---|---|---|
| Time (h) | t | 3 | 18 |
| Temperature (°C) | T | 100 | 150 |
| Equivalents of reducing agent (CR/CCuCl2) | [R] | 1 | 5 |
| Type of reducing agent | {R} | Asc | Glu |
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