Table 2.

Summary of the considered parameter constellations for performance comparison

Parameter	Values
Significance level $\alpha$	0.025
Type-II error $\beta$	0.2
Effect $\delta$	$[-0.4,0.8]$
Standard deviation $\sigma$	1
Maximum sample size per arm $n_{\mathit{max}}$	200
Interim information fraction $I_1$	$\{0.3,0.4,0.5\}$
Pipeline information fraction $I_{{\mathrm{\Delta }}_t}$	$\{0.1,0.2,0.3\}$
Spending functions	O’Brien-Fleming-type spending, Pocock-type spending