Table 1.
The cost-effectiveness decision tree model input parameters summary
| Input parameters | Mean value | Minimum | Maximum |
|---|---|---|---|
| A. Cost input parameters (L.E): | |||
| Total cost of ICU stay (No PCT guidance) | 240,000 | 80,000 | 400,000 |
| Total cost of ICU stay (With PCT guidance) | 280,000 | 140,000 | 420,000 |
| Total cost of Mechanical Ventillation (MV) (No PCT guidance) | 11,100 | 7200 | 15,000 |
| Total cost of Mechanical Ventillation (MV) (With PCT guidance) | 9250 | 6000 | 12,500 |
| Total cost of antibiotics regimen (No PCT guidance) | 49,640 | 20,570 | 69,020 |
| Total cost of antibiotics regimen (With PCT guidance) | 35,040 | 14,520 | 48,720 |
| Total cost of Hemodialysis (HD) (No PCT guidance) | 21,000 | 4050 | 36,000 |
| Total cost of Hemodialysis (HD) (With PCT guidance) | 14,000 | 3700 | 24,000 |
| Total cost of anaerobic culture | 325 | 191 | 460 |
| Total cost of blood cuture | 790 | 408 | 1170 |
| Toal cost of sputum culture | 215 | 95 | 335 |
| Total cost of urine culture | 215 | 95 | 335 |
| Total cost of Lab. PCT investigation | 10,290 | 5320 | 15,260 |
| Total cost of ward stay (No PCT guidance) | 84,000 | 28,000 | 140,000 |
| Total cost of ward stay (With PCT guidance) | 80,000 | 40,000 | 120,000 |
| B. Incident probabilities: | |||
| Probability of In-hospital mortality (No PCT guidance) | 0.298 | 0.235 | 0.364 |
| Probability of In-hospital mortality (With PCT guidance) | 0.218 | 0.171 | 0.264 |
| C. Outcome input parameters (QALY): | |||
| One year utility score (No PCT guidance) | 0.47 | 0.43 | 0.51 |
| One year utility score (With PCT guidance) | 0.52 | 0.49 | 0.54 |
A. Cost data were collected using Delphi approach from twenty panelists of ICU consultants
B. Incident probabilities were obtained through extensive systematic literature review
C. Outcome input parameters (QALY) were obtained through extensive systematic literature review