Thermodynamic data for homoternary complexes.

Host	Amino acid, peptide, or protein	K ter (M−2)	ΔH (kcal mol−1)	−TΔS (kcal mol−1)
Q8a	Tryptophan	6.9 × 107	−17.1	6.3
Q8a	Phenylalanine	1.1 × 108	−15.2	4.2
Q8a	All 18 other amino acids	ndm	nrn	nr
Q8b	H-Trp-Gly-Gly-OH	3.6 × 109	−22.8	9.7
Q8b	H-Gly-Trp-Gly-OH	nd	nr	nr
Q8b	H-Gly-Gly-Trp-OH	nd	nr	nr
Q8b	H-Phe-Gly-Gly-OH	1.5 × 1011	−29.6	14.2
Q8b	H-Gly-Phe-Gly-OH	nd	nr	nr
Q8b	H-Gly-Gly-Phe-OH	nd	nr	nr
Q8b	H-Tyr-Gly-Gly-OH	nd	nr	nr
Q8b	H-Gly-Tyr-Gly-OH	nd	nr	nr
Q8b	H-Gly-Gly-Tyr-OH	nd	nr	nr
Q8b	H-His-Gly-Gly-OH	nd	nr	nr
Q8b	H-Gly-His-Gly-OH	nd	nr	nr
Q8b	H-Gly-Gly-His-OH	nd	nr	nr
Q8c	H-Phe-Gly-Gly-OH	2.3 × 1010	−25.3	11.2
Q8c	H-Phe-Gly6-OH	4.4 × 109	−23.0	9.8
Q8d	H-Ala-Glu-Phe-Arg-His-NH2	3.0 × 1010	−15.3	0.9
Q8d	H-Leu-Val-Phe-Ile-Ala-NH2	7.7 × 109	−9.0	4.5
Q8d	H-Val-Ile-Phe-Ala-Glu-NH2	1.6 × 1013	−20.8	2.8
Q8e	H-Phe-Leu-NH2	1.9 × 1011	−26.7	11.3
Q8e	H-Tyr-Ala-Leu-NH2	8.7 × 107	−18.1	7.3
Q8f	H-Phe-Gly-Gly-Gly-Cys-OH	2.3 × 1013	−21.8	6.2
Q8g	H-Phe-Gly-Gly-OH	1.7 × 1012	nr	nr
Q8h	H-Tyr-His-OH	2.4 × 108	nr	nr
Q8i	mCFP-FGG	2.5 × 1013	−29.3	10.6
Q8j	Caspase-9-FGG	2.7 × 1012	−23.7	5.3
Q8k	GST-FGG	2.9 × 1012	−13.2	−3.8
Q8l	Aβ 4–16	5.5 × 1010	nr	nr
Q8l	Aβ 1–16	nd	nr	nr

^a10 mM sodium phosphate, pH 7.0, 300 K.³²

^b10 mM sodium phosphate, pH 7.0, 300 K.¹⁸

^cPBS: 10 mM sodium phosphate, 1.8 mM potassium phosphate, 137 mM NaCl, 2.7 mM KCl, pH 7.4, 298 K.⁴⁹

^d10 mM sodium phosphate, pH 7.4, 298 K.⁵⁰

^e10 mM sodium phosphate, pH 7.0, 298 K.⁵¹

^fPure water, 298 K.⁵²

^gPure water, 298K.⁵³

^h50 mM sodium acetate, pH 4.74.⁵⁴

ⁱMonomeric cyan fluorescent protein modified with N-terminal FGG, 10 mM sodium phosphate, pH 7.0, 303 K.⁵⁵

^jCaspase-9 modified with N-terminal FGG, 10 mM sodium phosphate, pH 7.0, 303 K.⁵⁶

^kGlutathione-S-transferase modified with N-terminal FGG, 20 mM sodium phosphate, 1 mM EDTA, pH 7.4, 298 K.⁵⁷

^l10 mM sodium phosphate, pH 7.4, 298 K.⁵⁸

^mNot detected.

ⁿNot reported. Putative binding sites are in bold.