Table 2.
Prediction of virulence factor genes of the Vibrio cholerae Strain CQ23-0008VC.
| Functional description | Virulence factor | Gene name |
|---|---|---|
| Adherence | Toxin-coregulated pilus (type IVB pilus) Type IV pilus |
MshB-mshN PilA-pilD |
| Antiphagocytosis | Capsular polysaccharide | CpsA-cpsD, cpsF, rmlD, wbfB wbfU, wbfV/wcvB, wbfY, wbjD/wecB wecA, wecC, wza, wzb, wzc |
| Chemotaxis and motility | Flagella | cheA, cheB, cheR, cheV, cheW, cheY, cheZ filM flaA-flaE, flag, flaI flgA-flgN flhA, flhB, flhF, flhG fliA, fliD-fliS flrA, flrB, flrC motA, motB, motX, motY |
| Enzyme | Metalloproteinase Neuraminidase |
hap/vvp nanH |
| Iron uptake | Enterobactin receptors Heme receptors Periplasmic binding protein-dependent ABC transport systems Vibriobactin |
irgA, vctA hasR, hutA, hutR vctC, vctD, vctG, vctP viuC, viuD, viuG, viuP vibA-vibF, vibH viuA, viuB |
| Quorum sensing | Autoinducer-2 Cholerae autoinducer-1 |
luxS cqsA |
| Secretion system | T3SS2 secreted effectors T3SS2 VAS effector proteins VAS type VI secretion system |
vopL vcrD2, vscC2, vscN2 hcp-2, vgrG-1, vgrG-2 vasA-vasK |
| Toxin | RTX toxin Thermolabile hemolysin Vibrio cholerae cytolysin |
rtxA, rtxB, rtxC, rtxD tlh hlyA |
| Serum resistance | LPS rfb locus (Klebsiella) | – |