TABLE 1.

Strategies for database search.

Database	Search strategy (February 2022, updated on August 2024)
Main databases
Embase https://www.embase.com	#1 “chronic obstructive lung disease”/exp OR “chronic obstructive lung disease” OR “chronic disease”/exp OR “chronic disease” OR “lung disease”/exp OR “lung disease”
	#2 “home care”/exp OR “home care” OR “hospital discharge”/exp OR “hospital discharge”
	#3 “hospital care”/exp OR “hospital care” OR “hospital cost”/exp OR “hospital cost” OR “hospital”/exp OR “hospital” OR “hospitalization”/exp OR “hospitalization”
	#4 “cost benefit analysis”/exp OR “cost benefit analysis” OR “cost effectiveness analysis”/exp OR “cost effectiveness analysis” OR “healthcare cost”/exp OR “healthcare cost” OR “cost”/exp OR “cost”
LILACS http://lilacs.bvsalud.org/	#1 (MH: “Pulmonary Disease, Chronic Obstructive” OR COPD)
	#2 (MH: “Cost-Benefit Analysis” OR “Cost-Effective*” OR MH: “Healthcare Economics and Organizations” OR MH: “Costs and Cost Analysis” OR MH: “Healthcare Costs”)
PubMed http://www.ncbi.nlm.nih.gov/pubmed	#1 “Pulmonary Disease, Chronic Obstructive”[Mesh] OR COPD OR “Chronic Disease*”[Mesh] OR “Lung Disease*”[Mesh] OR “Lung Diseases, Obstructive”[Mesh]
	#2 “Home Care Services”[Mesh] OR “Home Care Agencies”[Mesh] OR “Home Nursing”[Mesh] OR “Home Health Nursing”[Mesh] OR “Home Treatment” OR “Hospital-At-Home” OR “Home Hospitalization” OR “Early Discharge” OR “Patient Discharge”[Mesh]
	#3 Hospital*[Mesh] OR “Hospital Care” OR “Health Centers” OR “Hospital Costs”[Mesh] OR “Hospitals, Chronic Disease”[Mesh] OR Hospitalization[Mesh] OR “Inpatient Hospital Care”
	#4 “Cost-Benefit Analysis”[Mesh] OR “Cost-Effective*” OR “Healthcare Economics and Organizations”[Mesh] OR “Fees and Charges”[Mesh] OR “Costs and Cost Analysis”[Mesh] OR “Healthcare Costs”[Mesh]
SciELO https://scielo.org/	#1 (“Pulmonary Disease, Chronic Obstructive” OR COPD)
	#2 (“Cost-Benefit Analysis” OR “Cost-Effective” OR “Healthcare Economics and Organizations” OR “Costs and Cost Analysis” OR “Healthcare Costs”)
Scopus http://www.scopus.com/	#1 TITLE-ABS-KEY (“Pulmonary Disease, Chronic Obstructive” OR COPD OR “Chronic Disease*” OR “Lung Disease*” OR “Lung Diseases, Obstructive”)
	#2 TITLE-ABS-KEY (“Home Care Services” OR “Home Care Agencies” OR “Home Nursing” OR “Home Health Nursing” OR “Home Treatment” OR “Hospital-At-Home” OR “Home Hospitalization” OR “Early Discharge” OR “Patient Discharge”)
	#3 TITLE-ABS-KEY (Hospital* OR “Hospital Care” OR “Health Centers” OR “Hospital Costs” OR “Hospitals, Chronic Disease” OR Hospitalization OR “Inpatient Hospital Care”)
	#4 TITLE-ABS-KEY (“Cost-Benefit Analysis” OR “Cost-Effective*” OR “Healthcare Economics and Organizations” OR “Fees and Charges” OR “Costs and Cost Analysis” OR “Healthcare Costs”)
Web of Science http://apps.webofknowledge.com/	#1 TS = (“Pulmonary Disease, Chronic Obstructive” OR COPD)
	#2 TS = (“Cost-Benefit Analysis” OR “Cost-Effective” OR “Healthcare Economics and Organizations” OR “Costs and Cost Analysis” OR “Healthcare Costs”)
Dedicated databases
NHS Economic Evaluation Database (NHS EED) https://www.crd.york.ac.uk/CRDWeb/	#1 COPD
	#2 “Home Care”
	#3 “Hospital Care”
Global Health Cost-Effectiveness Analysis Registry (GH CEA) https://cevr.tuftsmedicalcenter.org/databases/cea-registry	#1 COPD
	#2 “Home Care”
	#3 “Hospital Care”
Gray literature
DansEasy https://easy.dans.knaw.nl/ui/home	#1 (“Pulmonary Disease, Chronic Obstructive” OR COPD)
	#2 (“Cost-Benefit Analysis” OR “Cost-Effective” OR “Healthcare Economics and Organizations” OR “Costs and Cost Analysis” OR “Healthcare Costs”)
ProQuest https://about.proquest.com/en/dissertations/	#1 (“Pulmonary Disease, Chronic Obstructive” OR COPD OR “Chronic Disease*” OR “Lung Diseases” OR “Lung Diseases, Obstructive”)
	#2 (“Home Care Services” OR “Home Care Agencies” OR “Home Nursing” OR “Home Health Nursing” OR “Home Treatment” OR “Hospital-At-Home” OR “Home Hospitalization” OR “Early Discharge” OR “Patient Discharge”)
	#3 (Hospital OR “Hospital Care” OR “Health Centers” OR “Hospital Costs” OR “Hospitals, Chronic Disease” OR Hospitalization OR “Inpatient Hospital Care”)
	#4 (“Cost-Benefit Analysis” OR “Cost-Effective” OR “Healthcare Economics and Organizations” OR “Fees and Charges” OR “Costs and Cost Analysis” OR “Healthcare Costs”)