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. 2024 Jul 10;18:1728. doi: 10.3332/ecancer.2024.1728

Table 2. All grade adverse events of TFD/TPI monotherapy or combined with bevacizumab.

All grade TFD/TPI + BEV (n) TFD/TPI (n) OR, IV, 95% CI p value I 2
Anemia 420 409 0.73 (0.54; 0.99) 0.04 0%
Neutropenia 420 409 1.44 (0.92; 2.26) 0.10 39%
Thrombocytopenia 420 409 1.72 (1.18; 2.50) <0.01 6%
Nausea 515 688 1.08 (0.67; 1.75) 0.74 74%
Vomiting 409 421 1.28 (0.88; 1.85) 0.19 0%
Diarrhea 317 588 1.09 (0.76; 1.55) 0.65 42%
Fatigue 2,789 6,909 1.12 (0.84; 1.50) 0.43 0%
Hypertension 2,675 6,812 2.78 (1.56; 4.94) <0.01 59%

Pooled results of all grade adverse events. n: number of patients analyzed; IV: inverse variance; CI: confidence interval