Extended Data Figure 8: Estimated survival curves for the concordant and discordant treatment groups among patients with CUP who received their initial treatments after the results of the OncoPanel sequencing were available to clinicians.

Similarly, we utilized Inverse Probability of Treatment Weighted (IPTW) Kaplan-Meier estimator for each survival curve while adjusting for patient covariates and left truncation until time of sequencing (see Methods). Statistical significance of the survival difference between the two groups was estimated by a weighted log-rank test. Refer to Supplementary Table S2 for demographic information on the cohort.