TABLE 1.
Tissue sample sources by contributing institutions and cohorts.
| Data contributor group | Participating cohorts | N |
|---|---|---|
| Columbia | Columbia ADRC | 61 |
| Biggs Institute Brain Bank | 6 | |
| Estudia Familiar de Influencia Genetica en Alzheimer (EFIGA) | 4 | |
| National Institute on Aging Alzheimer's disease Family Based Study (FBS) | 3 | |
| Washington Heights, Inwood Columbia Aging Project (WHICAP) | 31 | |
| Emory | Emory Goizueta ADRC | 112 |
| Mt Sinai Brain Bank | 22 | |
| UPenn CNDR | 22 | |
| Mayo Clinic | Mayo Clinic Brain Bank | 268 |
| Banner Sun Health Research Institute | 43 | |
| University of Florida (UFL) | 20 | |
| Mt. Sinai | Mt. Sinai Brain Bank | 88 |
| Rush | Clinical Core (CLINCOR) | 67 |
| Latino Core Study (LATC) | 1 | |
| Minority Aging Research Study (MARS) | 32 | |
| Religious Orders Study (ROS) | 56 | |
| Memory and Aging Project (MAP) | 72 | |
| Additional samples sourced from AMP‐AD 1.0 to balance proteomics batches a | ||
| Mt. Sinai | Mt. Sinai Brain Bank | 114 |
| Rush | ROS | 145 |
| MAP | 48 | |
Abbreviation: AD, Alzheimer's disease; ADRC, Alzheimer's Disease Research Center; AMP‐AD, Accelerating Medicines Partnership in Alzheimer's Disease; UPenn CNDR, University of Pennsylvania Center for Neurodegenerative Disease Research; WGS, whole genome sequencing.
a
These individuals were sourced from AMP‐AD 1.0 tissue repositories and added to the Diverse cohort samples for proteomics processing only, to fully balance batches by race, ethnicity, age, sex, diagnosis (AD), and tissue region. All individuals have accompanying WGS data generated during the AMP‐AD 1.0 initiative; WGS biospecimen data for these individuals can be found in the AD Knowledge Portal (syn53352733).