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. 2024 Sep 6;20(10):6881–6895. doi: 10.1002/alz.14154

TABLE 2.

Commonality analysis predicting conversion from cognitively normal to mild cognitive impairment.

AD biomarkers versus digital biomarkers: cognitively normal to mild cognitive impairment
Measure Coefficient Percentage variance explained (%)
Cortical Aβ 0.00765 18.75
EC tau 0.00063 1.55
Digital cognitive battery 0.02295 56.25
Cortical Aβ and EC tau 0.00289 7.08
Cortical Aβ and digital cognitive battery 0.00330 8.09
EC tau and digital cognitive battery 0.00093 2.27
Cortical Aβ and EC tau and digital cognitive battery 0.00245 6.01
Digital cognitive tasks: cognitively normal to mild cognitive impairment
Measure Coefficient Percentage variance explained (%)
OCL 0.02195 54.34
OBT 0.00001 0.02
Identification 0.00214 5.30
Detection 0.00008 0.20
OCL and OBT 0.00003 0.08
OCL and Identification 0.00163 4.03
OBT and Identification 0.00082 2.04
OCL and Detection 0.00061 1.52
OBT and Detection 0.00001 0.01
Identification and Detection 0.00179 4.43
OCL and OBT and Identification 0.00190 4.71
OCL and OBT and Detection −0.00003 −0.07
OCL and Identification and Detection 0.00355 8.80
OBT and Identification and Detection 0.00147 3.64
OCL and OBT and Identification and Detection 0.00442 10.95

Abbreviations: Aβ, amyloid beta; OBT, one‐back task; OCL, One Card Learning.