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. 2024 Oct 14;16(1):2410316. doi: 10.1080/19420862.2024.2410316

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© 2024 23andMe. Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 1. — Crystal structure of 23ME-00610-Fab bound to hCD200R1-iso4-ref reveals binding interface. (a) Structure of 23ME-00610-Fab:hCD200R1 complex shown in ribbon. hCD200R1 is in light blue color. 23ME-00610 heavy chain is in magenta, and light chain in green. (b) Zoom-in view of the binding interface with 23ME-00610 is represented as a surface. R67 in hCD200R1, shown as a stick, protrudes into a pocket cavity created at the intersection of the heavy (HC) and light (LC) chains of 23ME-00610.